Vitamin E

Vitamin E mainly functions in the body as an antioxidant, which helps prevent damage caused by free radicals – rogue forms of oxygen that wreak havoc with the fats found in the outer layer, or membrane, of all cells.

Vitamin E supports heart and brain health by preventing the oxidation of low-density lipoproteins (LDL, or “bad” cholesterol) by free radicals. LDLs take cholesterol away from the liver, where they are made, to the tissues of the body, with the intent of dumping their cholesterol there. Oxidized LDLs are thought to raise the risk of clogged arteries that block oxygen-rich blood from the heart and brain. And when the cells that line the interior of blood vessels get the vitamin E they need, they’re better able to resist plaque buildup. Vitamin E is involved in a process that dilates blood vessels, boosting blood flow and reducing the stickiness of red blood cells, thereby cutting the risk of blood clots that block the flow of blood.
Brain cells are particularly prone to oxidative stress. Oxidative stress may play a role in conditions that affect the brain, including dementia, but more research is needed to shore up the connection between vitamin E and disease prevention and management.

Vitamin E can prevent the oxidation of the fatty portion of the cell membranes in the lens of your eye, helping to support eye health.

Vitamin E also plays a role in immune function.
As nutrients go, vitamin E is more complex than most: there are actually eight forms of vitamin E found naturally in foods, each with a different level of biological activity in the body. However, alpha-tocopherol is the only form that is known to meet the body’s requirement for vitamin E, and it is the form on which the recommended dietary allowance (RDA) is based.*

Relevant Health Areas

How much do I need?
 
Recommended Dietary Allowance
Tolerable Upper Intake Level
 
 
 
IU - International Units
Values determined by the Institute of Medicine (IOM)
 
Suggested Supplements
Best Bets
Also Supports
fruits Suggested Foods

Most vitamin E is found in foods with a high fat content.

If you take blood-thinning medication or other over-the-counter drugs, you may need to avoid large doses of vitamin E. Talk with your doctor or pharmacist about the possible interaction between vitamin E and the medications you take on a regular basis.

  1. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium and Carotenoids. Washington, D.C.: National Academy Press, 2000.

  2. United States Department of Agriculture. Agricultural Research Serving. Nutrient Data Laboratory. http://www.ars.usda.gov/main/site_main.htm?modecode=12-35-45-00

  3. Linus Pauling Institute. Micronutrient Information Center. Vitamin E. http://lpi.oregonstate.edu/infocenter/vitamins/vitaminE

  4. National Institutes of Health. Office of Dietary Supplements. Vitamin E. Dietary Supplement Fact Sheet. http://ods.od.nih.gov/factsheets/vitamine

  5. Maras JE, Bermudez OI, Qiao N, Bakun PJ, Boody-Alter EL, Tucker KL. Intake of alpha-tocopherol is limited among US adults. J Am Diet Assoc. 2004;104(4):567-575.

  6. Meydani SN, Meydani M, Blumberg JB, et al. Vitamin E supplementation and in vivo immune response in healthy elderly subjects. A randomized controlled trial. JAMA. 1997;277(17):1380-1386.

Vitamin E deficiency is rare in the United States, but marginally low intakes are common. Studies suggest that more than 90% of Americans do not meet the daily recommended amount of vitamin E. Vitamin E is found in fatty foods, and those who follow a very low fat diet may come up short for the suggested amount of vitamin E. In fact, it may be difficult to get the vitamin E you need from food alone without increasing your fat intake above the recommended levels, so you may want to consider taking a multivitamin to help meet your vitamin E requirements.

Higher levels of vitamin E may be beneficial for certain populations. Some experts in vitamin E research recommend taking 200 IU per day of supplemental vitamin E.

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